“Our findings counter the idea that Ebola virus infection is immunosuppressive, at least in the patients we were able to study,” Anita McElroy, MD, assistant professor of pediatrics at Emory University School of Medicine, said in a press release. “They also demonstrate the value that supportive care may have in enabling the immune system to fight back against Ebola virus infection.”
McElroy and colleagues examined the T- and B-cells of four Ebola survivors to gauge the immune system’s response to Ebola virus infection. Using the CDC’s biosafety level-4 laboratory space, they determined the frequency of activated immune cells, phenotyped activated CD8 T-cells, and measured the kinetics of each patient’s response.
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