Early steroid use for severe COVID-19 associated with fewer deaths in serious cases

Early steroid use for severe COVID-19 tied to fewer deaths CIDRAP

JAMA Network Open has published a new US national cohort study demonstrating that early administration of the steroid dexamethasone was associated with significantly reduced odds of mortality or discharge to hospice in those requiring supplemental oxygen or mechanical ventilation and/or extracorporeal membrane oxygenation.

The effect was not seen, however, in patients who did not require supplemental oxygen or noninvasive positive-pressure ventilation.

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