Treatments

Study: Paxlovid safe, effective in pregnancy EmiliaU / iStock CIDRAP

A study based on 211 pregnant women given the antiviral drug nirmatrelvir and ritonavir (Paxlovid) during pregnancy for acute COVID-19 infections shows no increased risk of adverse events in the women or their babies and a reduced risk of complications called the maternal morbidity and mortality index (MMMI).

The findings, published today in Nature Medicine, suggest the drug is safe to use in pregnancy and is effective in reducing MMMI risk but not COVID-related hospitalizations.

...

As RSV cases tick up, CDC warns that a key drug to keep babies safe is in short supply The CDC's alert says the highest dosage of the drug, called Beyfortus, is in limited supply. NBC News

... The agency told doctors to prioritize getting those doses to infants at the highest risk of severe RSV, including infants younger than 6 months and those with underlying conditions. The CDC also advised doctors to preserve 50 mg doses for infants who weigh less than 11 pounds.

Pfizer more than doubles price of lifesaving Covid-19 medication Paxlovid as US transitions out of pandemic phase | CNN The price of the lifesaving Covid-19 antiviral medication Paxlovid will more than double as the United States transitions out of the emergency phase of the pandemic, drugmaker Pfizer said Wednesday. Meg Tirrell CNN

The list price, before insurance, will be $1,390 for a five-day course, Pfizer said in a statement. That’s 2.6 times higher than the $530-per-course price paid by the US government, which provided Paxlovid free to patients during the pandemic. The Wall Street Journal first reported the new price.