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Zoloft Could Be a Treatment for Ebola Virus

Researchers have identified two FDA-approved drugs that may be effective against the Ebola virus. This could shorten the time for developing new treatments.

HEALTHLINE NEWS  by  Shawn Radcliffe                                                         June 3, 2015

With a fast-moving epidemic like Ebola, doctors need to make use of every tool at their disposal. This includes giving a second life to already-approved drugs....

One research team is hoping to ease the epidemic by shortening the lengthy drug development process.

Their approach? Sifting through hundreds of existing drugs and other compounds for ones that might work against the Ebola virus....

Additional screening narrowed the list down to two potential drug candidates: Bepridil, a calcium channel blocker used to treat heart disease, and sertraline, an antidepressant more commonly known as Zoloft.

Both drugs are already approved by the FDA, although not for use against the Ebola virus.

Read complete story.

http://www.healthline.com/health-news/zoloft-could-be-a-treatment-for-ebola-virus-060315#1

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Ebola outbreak thrusts MSF into new roles

 Relief agency sees its mission expanding after leading response to West Africa epidemic.

NATURE by  Erika Check Hayden                          June 3, 2015

GENEVA -- Joanne Liu, president of Médecins Sans Frontières (MSF), is not overly concerned with diplomacy. Participating in a panel in Geneva, Switzerland, on 20 May with officials from the United Nations, the World Health Organization (WHO), Liberia and Sierra Leone, she propped her head on her hand, stared into space and rolled her eyes during another speaker’s remarks. When she spoke, she excoriated the world for leaving West Africa vulnerable to the largest Ebola epidemic in history. “We’re failing, guys,” she said.

Joanne Liu visiting an MSF trauma centre in Kunduz, Afghanistan.

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New Thinking on Countering Outbreaks

                                                        

If Ebola has taught us anything, it is that there is room for innovation in the way we respond to outbreaks.

medium.com - by Paul G. Allen - April 30, 2015

It has been more than a year since we began tackling this latest epidemic and, while significant progress has been made, there are still challenges to be overcome and gaps to be filled. . . .

. . . Just last week, I partnered with Skoll Global Threats Fund and USAID to host the Ebola Innovation Summit — an interactive event, designed to bring new tools, people, ways of thinking and ultimately innovations to the forefront.

The event drew a diverse group of people from around the world — from the tech and private sectors to nonprofits, government and academia. The collective commitment of this group is a great example for how we should collaborate to tackle global problems like Ebola.

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Ban to convene international Ebola recovery conference in New York

UN NEWS CENTRE                                                                                June 2, 2015

To help mobilize needed resources “in the last mile of the response” against the Ebola outbreak and to start the affected West African countries on the path of early recovery, United Nations Secretary-General Ban Ki-moon today announced that he will convene an international conference next month.
In Sierra Leone, local health workers plan for the day ahead, as they continue their vigilance against Ebola. Photo: WHO/S. Aranda

“All of your investments, all of the sacrifices and lives lost, and all of the risks that the relief workers took would be squandered if the outbreak recurs,” Mr. Ban cautioned in his remarks to an informal plenary of the UN General Assembly on the Organization’s Ebola response efforts.

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UNMission for Ebola Emergency Response (UNMEER) External Situation Report 1 June 2015

UNMission for Ebola Emergency Response (UNMEER) External Situation Report  June 1,2015
KEY POINTS:
 
Further preparedness measures taking place in Guinea Bissau, following newly confirmed Ebola
cases in adjacent border areas of Guinea
.
Response efforts continue in Boké prefecture, as preparations for the forthcoming sensitisation and
early Ebola case search campaign progress in Dubréka.
...
UNMEER Comment: In Kamsar (Boké prefecture, Guinea)...: the number of burial teams may still
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Ebola threat to Guinea Bissau rises as border zone heats up

REUTERS                                                                                                    June 2, 2015

DAKAR --Violent protests against Ebola controls in a north Guinea town have prompted the Red Cross to withdraw workers, undermining efforts to stop the spread of Ebola into neighbouring Guinea Bissau.

 The Ebola epidemic was detected in Guinea over a year ago and has since killed more than 11,000 people in West Africa.

 But in a huge relief to officials and aid workers, it has not yet spread to Guinea Bissau, whose health system is deemed vulnerable even by low regional standards.

 Now, a spike in new cases in Guinea's Boke border province combined with violent resistance to efforts to control it there are stoking concerns it could spread.

Read complete story.

http://www.firstpost.com/world/ebola-threat-to-guinea-bissau-rises-as-border-zone-heats-up-reuters-2274104.html

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UN Official Says Ebola Will End in Sierra Leone in Weeks

ASSOCIATED PRESS by Edith M. Lederer                                           June 1, 2015

The U.N. Ebola chief said Monday he believes "it's only a matter of weeks" before the Ebola outbreak in Sierra Leone ends, but stopping the deadly disease in Guinea will take more time because in some areas unsafe traditions still hold sway over what's good for people's health.

Dr. David Nabarro stressed in an interview with The Associated Press on Monday that the Ebola epidemic "absolutely isn't over" though Liberia has been Ebola free since May 9.

"We have cases occurring, not in huge numbers but enough to be very disturbing, in Sierra Leone and in Guinea," he said, and the situation in Guinea is especially troubling because surprise cases have been popping up that are not part of known chains of transmission.

Read complete story.
http://abcnews.go.com/Health/wireStory/official-ebola-end-sierra-leone-weeks-31457174

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Health worker Ebola infections in Guinea, Liberia and Sierra Leone : WHO Report


Publication details

 Number of pages: 16
Publication date: May 2015
Languages: English
WHO reference number: WHO/EVD/SDS/REPORT/2015.1

Overview

 This preliminary report summarizes the impact of the Ebola epidemic on the health workforce of Guinea, Liberia and Sierra Leone. It investigates the determinants of infection and describes safe practices put in place to protect health workers during the epidemic. The report covers the period from 1 January 2014 to 31 March 2015 and is presents findings from the 815 confirmed and probable cases for whom individual case reports were available.

The Ebola epidemic has taken a heavy toll on the already scarce health workforce. Among the health workers for whom final outcome is known, two-thirds of those infected died. Preliminary analysis shows that, depending on their occupation in the health service, health workers are between 21 and 32 times more likely to be infected with Ebola than people in the general adult population. With higher risks of exposure in caring for others, health workers were disproportionately impacted and traumatised by Ebola.

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Did Authorities Use the Wrong Approach to Stop Ebola?

A new study suggests there was a better way to respond to the Ebola outbreak

TIME MAGAZINE by Alexandra Sifferlin                                                      May 26, 2015

It’s known that the response to the most recent Ebola outbreak, which as of Tuesday had infected more than 27,000 people and killed 11,130, was far too slow. Now, a new studysuggests that even once they got started, their approach to curbing the spread wasn’t the most efficient or effective.Read complete story.

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Doctors Link Risky Burials to Ebola Rise in West Africa

          

nytimes.com - by Adam Nossiter - May 19, 2015

Only days after declaring the lowest number of new Ebola cases in Guinea and Sierra Leone this year, officials at the World Health Organization said Tuesday that there had been a nearly fourfold increase during the most recent week of reporting, to about 35 new cases.

With Liberia, the other West African nation at the center of the epidemic, being declared free of Ebola this month, the recent drop in infections in Sierra Leone and Guinea had offered hope that the worst Ebola outbreak in history might end soon. . . .

. . . Health officials said that sharp falls and rises were normal as an epidemic approached its end. But they also said that some persistent risky practices, like unsafe burials of Ebola victims in Guinea, had contributed to the rise.

(READ COMPLETE ARTICLE)

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