As Ebola Rages, Poor Planning Thwarts Efforts

NEW YORK TIMES --by Jeffrey Gettleman                      Dec. 7, 2014

KERRY TOWN, Sierra Leone —On a freshly cleared hillside outside the capital, where the trees have been chopped down and replaced with acres of smooth gravel, the new Ebolatreatment center seems to have everything. There are racks of clean pink scrubs and white latex boots, bathrooms that smell like Ajax, solar-powered lights, a pharmacy tent, even a thatch-roofed hut to relax in.

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Cuban Ebola patient recovers after treatment in Geneva

REUTERS                                                                                                                                      Dec. 2014
                   
GENEVA-- Cuban doctor who received experimental treatment for Ebola in a Geneva hospital has made a full recovery and left Switzerland to be reunited with his family, the hospital said on Saturday.

Felix Baez, 43, was one of 256 Cuban doctors and nurses who went to West Africa to treat patients from the worst outbreak of the virus on record...

Soon after arriving in Geneva, Baez received the Canadian experimental treatment ZMab, a precursor to the Ebola drug ZMapp, which has been used to treat several U.S. patients...

A hospital spokeswoman said he received both ZMab and the untested flu drug favipiravir, made by Japan's Fujifilm, which the WHO has included on a list of potential Ebola treatments

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http://www.reuters.com/article/2014/12/06/us-health-ebola-cuba-idUSKBN0JK0BN20141206

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What Ebola can teach us about a new bubonic plague outbreak in Africa

THE WEEK -- by S.E. Smith                                                                                                     Dec. 5, 2014
While West Africa battles Ebola, another outbreak is striking just across the continent. In Madagascar, cases of plague are erupting in the small village of Mandritsara and the disease is spreading to neighboring communities. The two outbreaks are related by more than simple surface similarities, though. In fact, fighting the first has provided an invaluable blueprint for containing the second.West Africa's Ebola outbreak could inform responders to Madagascar's plague cases.

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Ebola in Graphics: The toll of a tragedy

THE ECONOMIST                                                                                                      Dec. 4, 2014

THE first reported case in the Ebola outbreak ravaging west Africa dates back to December 2013, in Guéckédou, a forested area of Guinea near the border with Liberia and Sierra Leone. Travellers took it across the border: by late March, Liberia had reported eight suspected cases and Sierra Leone six. By the end of June 759 people had been infected and 467 people had died from the disease, making this the worst ever Ebola outbreak. The numbers keep climbing. As of November 30th, 17,145 cases and 6,070 deaths had been reported worldwide, the vast majority of them in these same three countries. Many suspect these estimates are badly undercooked.

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http://www.economist.com/blogs/graphicdetail/2014/12/ebola-graphics

Link to an interactive map of the virus's current global reach:

http://www.economist.com/blogs/graphicdetail/2014/12/interactive-ebola-map

 

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Doctors Try Survivors’ Blood to Treat Ebola

Clinical Trials Are Being Launched in Africa but Face Challenges in Designing Ethical Studies, Compensating Donors

WALL STREET JOURNAL                                                                                                    Dec. 5, 2014
by Betsy McKay in Atlanta, David Gauthier-Villars in Conakry, Guinea, and Patrick McGroarty in Monrovia, Liberia

...Nearly a year after Ebola began spreading in West Africa, and with a proven drug or vaccine still far off, researchers are launching clinical trials on a product at hand: the blood of survivors.

 They want to determine whether so-called convalescent plasma or serum, chock full of antibodies, can help fight off the disease. But they face a number of complexities in carrying out the trials, including persuading survivors to participate....

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2 More Sierra Leonean Doctors Die of Ebola

ASSOCIATED PRESS by CLARENCE ROY-MACAULAY         Dec. 6, 2014

FREETOWN --Two more Sierra Leonean doctors have died from Ebola, further depleting the West African country's ability to respond to the devastating outbreak, health officials said Saturday.

The deaths bring the number of Sierra Leonean doctors killed by Ebola to nine.

Dr. Thomas Rogers, who had worked at Connaught Hospital in the capital, died Friday, according to Chief Medical Officer Dr. Brima Kargbo. Dr. Dauda Koroma also died Friday, said Jonathan Abass Kamara, a spokesman for the Health Ministry.

In all, 11 Sierra Leonean doctors have been infected; one has been cured and another is still in treatment.

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http://abcnews.go.com/Health/wireStory/8th-sierra-leonean-doctor-dies-ebola-27410480

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Is Ebola Taking a Heavier Toll on Women?

VOICE OF AMERICA  by Carol Guensburg                                                                                 Dec. 5, 2014
The Ebola virus, indiscriminate and opportunistic, has infected more than 17,000 people in West Africa, the World Health Organization reports. But some observers fear the epidemic may be exacting an especially heavy toll on women and girls.    

Its impact goes well beyond the disease itself, amplifying females’ vulnerabilities, exploiting their limits within traditional societies, and motivating responses of strength and resilience.

Fatmata Sowa, 28, is among the few women who've joined the Red Cross safe and dignified burial teams in Sierra Leone. ( Lisa Pattison / IFRC)

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Nigerian and British Ebola volunteers fly into Liberia, Sierra Leone

Additonal  Nigerian and British health workers arrive in Liberia and Sierra Leone to help counter Ebola

(Two stories, scroll down)

REUTERS  by James Harding Giahyue and Umaru Fofana   Dec. 5, 2014
MONROVIA/FREETOWN --More than 175 Nigerian medics arrived in Liberia and Sierra Leone on Friday to join the fight against Ebola, the first of 600 volunteers promised by the regional giant which contained its own outbreak earlier this year.

An army medic teaches NHS staff how to dispose of potentially contaminated waste last month, before their deployment to Sierra Leone. Photograph: Simon Davis/AFP/Getty Images

The medics will boost weak local health systems that are also struggling to contain other preventable diseases as Ebola discourages people from going to clinics for fear of contracting the fever.

"This is the African spirit you are showing, this is the Nigerian spirit,” Nigeria's ambassador to Liberia, Chigozie Obi-Nnadozie, told 76 Nigerian medics who landed there.

Another 100 volunteers landed in Freetown, Sierra Leone. Months into the Ebola response, experts say they are still short of medical personnel to staff treatment centers.

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Sierra Leone Seeing 80-100 New Ebola Cases Daily

ASSOCIATED PRESS by EDITH M. LEDERER                                                                             Dec. 5, 2014

UNITED NATIONS -- Sierra Leone said Friday that between 80 and 100 new cases of Ebola are being reported every day and the country now hardest-hit by the deadly virus desperately needs over 1,000 beds to treat victims.

Sierra Leone's Finance Minister Kaifalah Marah painted a grim picture to the U.N. Economic and Social Council Friday of the challenges facing his West African nation which failed to meet a World Health Organization interim goal of isolating 70 percent of Ebola patients and safely burying 70 percent of victims by Dec. 1.

The two other hard-hit countries, Liberia and Guinea, did meet the deadline, and the U.N.'s Ebola chief Dr. David Nabarro said the number of new cases in Liberia has dropped from 60 per day in September to 10 per day. ...

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International UN Peacekeeper in Liberia Tests Positive for Ebola

THE ASSOCIATED PRESS By JONATHAN PAYE-LAYLEH and MIKE CORDER                                                Dec. 5, 2014

MONROVIA- A U.N. peacekeeper who contracted Ebola in Liberia will be flown to the Netherlands for treatment, a Dutch Health Ministry spokeswoman said Friday.

The Nigerian soldier is expected to arrive in the Netherlands this weekend and will go into isolation at the University Medical Center Utrecht, according to Inge Freriksen.

This is the third infection for the mission, which comprises about 7,700 troops and police. The previous two died.

Sixteen people who came into contact with the Nigerian soldier have been quarantined, the mission said.

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http://abcnews.go.com/International/wireStory/peacekeeper-liberia-tests-positive-ebola-27383914

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Number of Ebola deaths could be cut by use of basic measures, say experts

THE GUARDIAN  by in Freetown and
Dec. 5, 2014

Basic medical interventions such as giving Ebola patients rehydration salts and fluids from bigger bags could cut the death toll in west Africa in the absence of a proven cure, experts in tropical diseases write on Friday in the Lancet.

The doctors say it is “therapeutic nihilism” to assume there is no treatment for Ebola just because there are no drugs. It is likely, they say, that many patients die because of dehydration.

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Cooler box-equipped motorbikes donated to UN will speed up Ebola testing process in West Africa

UNITED NATIONS NEWS CENTRE                                                                             Dec. 4, 2014
Four hundred motorbikes equipped with cooler boxes will help speed up deliveries of blood samples to laboratories from remote areas of Guinea, Liberia and Sierra Leone and reduce the waiting time for Ebola test results, thanks to a donation today from Germany to the United Nations.

Four hundred cooler box-equipped motorbikes for the Ebola Response were officially handed over to the UN Humanitarian Response Depot by German Ambassador to Ghana Ruediger John, and will be used to bring blood samples to labs in the most affected areas of Sierra Leone, Liberia, and Guinea. UNMEER Photo/Martine Perret

At UN Headquarters, meanwhile, UN Secretary-General Ban Ki-moon told reporters that the immediate priorities of the United Nations are to stop the virus and to treat all the people who have Ebola. “We have to ensure that all essential services are provided, and also we have to help them preserve their social and political stability, and keeping a further outbreak from happening.”

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U.S. is weighing more aid to fight Ebola in Sierra Leone

                                             Dec. 14, 2014

The United States is weighing an increase in aid, including a possible military component, to help fight the Ebola outbreak in Sierra Leone, the country in West Africa where the deadly virus is spreading the fastest, officials said Thursday.

“We are looking at what more can be done in Sierra Leone, recognizing that is the forefront when it comes to the virus, and we’re clearly looking at all options,” said a senior administration official who spoke on the condition of anonymity because he was not authorized to discuss policies that are being formulated.

“Nothing is off the table,” he said. “If we determine that only the U.S. military with its unique capabilities can bring this under control, it is something we are willing to consider.”

Among the options is shifting foreign medical teams from­ ­Liberia to Sierra Leone, said ­Andrew Weber, the State Department’s deputy coordinator for Ebola response, in an interview.

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What Ebola Is Teaching Us About Hard Trends

WIRED     Essay by David Burris                                                                                        Dec. 14, 2014

...Deadly and infectious viruses such as Ebola are an inevitable and unavoidable fact of nature. In other words, they are examples of a Hard Trend. And they demand new innovations in order to combat them.

...the deadly force of Ebola is the kind of imminent threat that inspires human minds to new heights. It teaches us that Hard Trends come at us fast and provide the catalyst to overcome inertia and bring about technological innovations.

NIAID/Flickr

Communication is key to mobilizing populations in countries affected by Ebola. In order to treat the sick and prevent the spread of the disease, healthcare workers need to be able to coordinate with people on the frontline and know where to send supplies. At the moment, telecommunications technologies are not keeping pace with the intense demands that Ebola creates.

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Ebola Free-for-All Could Trigger Bad Science and Wasted Efforts

Everybody and his uncle, it seems, has an idea of something that might work to cure people infected with the deadly virus

 SCIENTIFIC AMERICAN    By Helen Branswell                        Dec. 4, 2014

When it comes to treatments for Ebola, there has been a nearly four-decade-long drought. Nothing in the medical arsenal attacks the virus directly....

 

 

 

Dr. John M. Dye, Jr., U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) Viral Immunology branch chief, works in a laboratory at the USAMRIID headquarters in Frederick, Maryland. Dr. Dye is leading a team that is conducting a study with nonhuman primates involving the experimental drug ZMapp, an experimental treatment for Ebola patients. Credit: CDC

 

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