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What Ebola can teach us about a new bubonic plague outbreak in Africa

THE WEEK -- by S.E. Smith                                                                                                     Dec. 5, 2014
While West Africa battles Ebola, another outbreak is striking just across the continent. In Madagascar, cases of plague are erupting in the small village of Mandritsara and the disease is spreading to neighboring communities. The two outbreaks are related by more than simple surface similarities, though. In fact, fighting the first has provided an invaluable blueprint for containing the second.West Africa's Ebola outbreak could inform responders to Madagascar's plague cases.

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Number of Ebola deaths could be cut by use of basic measures, say experts

THE GUARDIAN  by in Freetown and
Dec. 5, 2014

Basic medical interventions such as giving Ebola patients rehydration salts and fluids from bigger bags could cut the death toll in west Africa in the absence of a proven cure, experts in tropical diseases write on Friday in the Lancet.

The doctors say it is “therapeutic nihilism” to assume there is no treatment for Ebola just because there are no drugs. It is likely, they say, that many patients die because of dehydration.

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Cooler box-equipped motorbikes donated to UN will speed up Ebola testing process in West Africa

UNITED NATIONS NEWS CENTRE                                                                             Dec. 4, 2014
Four hundred motorbikes equipped with cooler boxes will help speed up deliveries of blood samples to laboratories from remote areas of Guinea, Liberia and Sierra Leone and reduce the waiting time for Ebola test results, thanks to a donation today from Germany to the United Nations.

Four hundred cooler box-equipped motorbikes for the Ebola Response were officially handed over to the UN Humanitarian Response Depot by German Ambassador to Ghana Ruediger John, and will be used to bring blood samples to labs in the most affected areas of Sierra Leone, Liberia, and Guinea. UNMEER Photo/Martine Perret

At UN Headquarters, meanwhile, UN Secretary-General Ban Ki-moon told reporters that the immediate priorities of the United Nations are to stop the virus and to treat all the people who have Ebola. “We have to ensure that all essential services are provided, and also we have to help them preserve their social and political stability, and keeping a further outbreak from happening.”

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What Ebola Is Teaching Us About Hard Trends

WIRED     Essay by David Burris                                                                                        Dec. 14, 2014

...Deadly and infectious viruses such as Ebola are an inevitable and unavoidable fact of nature. In other words, they are examples of a Hard Trend. And they demand new innovations in order to combat them.

...the deadly force of Ebola is the kind of imminent threat that inspires human minds to new heights. It teaches us that Hard Trends come at us fast and provide the catalyst to overcome inertia and bring about technological innovations.

NIAID/Flickr

Communication is key to mobilizing populations in countries affected by Ebola. In order to treat the sick and prevent the spread of the disease, healthcare workers need to be able to coordinate with people on the frontline and know where to send supplies. At the moment, telecommunications technologies are not keeping pace with the intense demands that Ebola creates.

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Sierra Leonean in US Sends Medical Supplies Home to Combat Ebola

voanews.com - by Deborah Block - Nov 26, 2014



On Thanksgiving day in the United States, Americans give thanks for their blessings. Among them is Bobby Smith, who emigrated to here 25 years ago from Sierra Leone. To give back, three years ago Smith began a small volunteer organization, Hope for Lives in Sierra Leone, to help the disadvantaged in his homeland -- one of the poorest countries in the world. As VOA’s Deborah Block reports, he now is sending medical supplies to help combat Ebola, which continues to devastate Sierra Leone.

http://www.voanews.com/media/video/sierra-leonean-in-us-sends-medical-supplies-home-to-combat-ebola/2535979.html

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Finding the Ebola virus’ vulnerable points

Three copies of the Ebola glycoprotein (blue) with antibodies (yellow) latched on to them. Picture by Stanfordby Shalini Saxena - Nov 30 2014 - http://arstechnica.com

We know what antibodies stop it in its tracks—we now know where they attach.

The latest Ebola outbreak has dwarfed any that have occurred since the discovery of the virus in 1976; previous outbreaks have had lethality rates of up to 90 percent. Yet no vaccines or therapies are currently approved for human use, which limits our ability to treat patients and contain the outbreak. Mixtures of monoclonal antibodies (see sidebar) are a potential treatment option that has been used experimentally.

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U.N. Mission Warns That Ebola Still Poses ‘Huge’ Global Threat

A mother and child stand atop their mattresses in a classroom now used as Ebola isolation ward on Aug. 15, 2014, in Monrovia, Liberiaby Elizabeth Barber - Dec. 1, 2014 - time.com

The U.N. mission is urging that the longer the disease is allowed to storm West Africa, the more likely it is that the virus will reappear elsewhere in the world.

The head of the U.N. Ebola mission in West Africa has said there is a “huge risk” of the Ebola outbreak expanding beyond the hard-hit region.

https://time.com/3611314/u-n-ebola-global-threat-anthony-banbury-bbc/

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WHO Says Liberia, Guinea Meeting Ebola Targets

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To halt Ebola's spread, researchers race for data

DISCOVER MAGAZINE    By Kari Lydersen                                                                              Dec. 2, 2014
.....redicting the trajectory of Ebola rather than playing catching-up could do much to help prevent and contain the disease. Some experts have called for prioritizing mobile treatment units that can be quickly relocated to the spots most needed. Figuring out where Ebola is likely to strike next or finding emerging hot spots early on would be key to the placement of these treatment centers.

But such modeling requires data, and lots of it.  And for stressed healthcare workers on the ground and government and non-profit agencies scrambling to combat a raging epidemic, collecting and disseminating data is often not a high priority.

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Locking Ebola out of Sierra Leone jails

IRIN                                                              Dec. 1, 2014

DAKAR--It is next to impossible to avoid physical contact in an overcrowded prison. In Sierra Leone, heavily congested jails and a worsening Ebola outbreak make a potentially lethal combination. So how do you keep inmates safe?

                          Decongesting prisons in Sierra Leone to lower Ebola threat.Photo: Hannah McNeish/IRIN

Some of the safeguards against the virus are: A 21-day quarantine for fresh detainees before joining the old timers; training prison health workers and inmate leaders on Ebola prevention; and providing health and safety education and equipment.

Such measures, and others, have so far helped keep the virus out of Sierra Leone’s 17 prisons and three juvenile offenders’ homes, said Mambu Feika, head of NGO Prison Watch Sierra Leone (PWSL), which is spearheading a three-month programme to prevent Ebola transmission in prisons.

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