For more than a month in 2015, a multidisciplinary team including infectious disease and critical care physicians and nurses, respiratory therapists and other specialists at the National Institutes of Health (NIH) treated a critically ill patient who had contracted Ebola virus disease in Sierra Leone. A new report by the medical caregivers details the clinical course of the 34-year-old American healthcare worker who was admitted to the NIH Special Clinical Studies Unit on day 7 of his illness. The patient survived his illness with intensive supportive care, despite multi-organ failure.
Upon admission to the NIH Clinical Center, the patient was enrolled in a clinical trial and was randomly assigned to receive optimized supportive care only. The trial's other arm included treatment with experimental therapies. In the first few days after admission, the patient's condition worsened dramatically and he experienced sequential organ failure, despite intensive supportive care that included maintenance of optimal fluid and electrolyte balances. His prognosis was poor.
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