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Increased physical activity associated with lower risk of severe COVID-19 --study

A South Korean study shows a complex relationship between moderate to vigorous physical activity (MVPA) and COVID-19, with a regular exercise habit linked to COVID-19 infection early in the pandemic but also associated with a significantly lower risk of developing severe symptoms. The study was published yesterday in JAMA Network Open.

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U.S. COVID Pandemic relief efforts failed to reach many immigrant families

Immigrant families living in the United States took some of the hardest economic hits during the COVID-19 pandemic, but benefited less from government assistance and relief programs than families with US-born caregivers.

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Opinion: The NIH has little to show for the $1 billion spent to study long Covid

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The National Institutes of Health hasn’t signed up a single patient to test any potential treatments — despite a clear mandate from Congress to study them. And the few trials it is planning have already drawn a firestorm of criticism, especially one intervention that experts and advocates say may actually make some patients’ long Covid symptoms worse.

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Two drug combination shows protection against severe COVID-19

Two new randomized, controlled trials published yesterday in the Annals of Internal Medicine describe how drug combinations lowered the risk of severe COVID-19, with one detailing use of the antidepressant fluvoxamine plus the corticosteroid budesonide, and the other outlining the monoclonal antibody duo amubarvimab plus romlusevimab.

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Mozambique Asks WHO for Additional Cholera Vaccine following Cyclone

Mozambique has asked the World Health Organization to supply an additional 2 million doses of a cholera vaccine as the country struggles to control a spreading outbreak.

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Early steroid use for severe COVID-19 associated with fewer deaths in serious cases

JAMA Network Open has published a new US national cohort study demonstrating that early administration of the steroid dexamethasone was associated with significantly reduced odds of mortality or discharge to hospice in those requiring supplemental oxygen or mechanical ventilation and/or extracorporeal membrane oxygenation.

The effect was not seen, however, in patients who did not require supplemental oxygen or noninvasive positive-pressure ventilation.

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