Liberia president to end Ebola state of emergency

ASSOCIATED PRESS                                         Nov. 13, 2014

By Jonathan Paye-Leyleh and Baba Ahmed

MONROVIA, Liberia (AP) — Liberia's president said Thursday she is lifting a state of emergency imposed to control an Ebola outbreak that has ravaged the country, as Mali raced to track down everyone who may have come into contact with three people now believed to have died of Ebola in its capital.

Also Thursday, Doctors Without Borders announced that accelerated clinical trials will be launched in West Africa to speed the search for a treatment for the virus that has killed more than 5,000 people.

In a nationwide address, Liberian President Ellen Johnson Sirleaf said enough progress has been made to lift emergency measures but added that the move does not mean the outbreak is over. There have been fewer Ebola cases in Monrovia, the capital, though fresh hotspots have emerged. One of those is near the border with Sierra Leone, which along with Guinea has also been hit hard by the disease.

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http://news.yahoo.com/medical-aid-group-host-3-ebola-clinical-trials-090631858.html

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The economics of Ebola

HOMELAND SECURITY NEWS WIRE                                                                                             Nov. 13, 2014
By Catherine de Fontenay
Economists are being called upon to estimate the costs of the Ebola epidemic to West Africa and elsewhere. Economists, however, should also play a part in estimating the likelihood of the disease spreading. Economics is the study of incentives, and many biological models of the spread of the disease may be underestimating the impact of individual incentives.

 Based on cost-benefit analysis, the potential costs of Ebola spreading are extremely high and the risks may be much higher than they are currently portrayed. Voters and donors should support greater efforts to end Ebola in West Africa. As International Monetary Fund director Christine Lagarde says, “real action” is needed to counter the outbreak. Without such action Ebola places the global economy at risk.

...If Ebola spreads throughout West Africa, the cost could rise to US$32.6 billion by the end of 2015.
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http://www.homelandsecuritynewswire.com/dr20141113-the-economics-of-ebola

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Are we asking the wrong questions about Ebola?

BBC NEWS MAGAZINE                                            NOV. 11, 2014

By Ben Carter

The Ebola virus has killed about 5,000 people since March - but one scientist who is studying the statistics says this is not the best figure to consider if we really want to understand the current state of the outbreak and how to beat it.

 

 

A total of 4,960 people have died from Ebola this year according to statistics released by the World Health Organisation on 4 November. More than half of those cases - 2,766 - were in Liberia.

But this cumulative figure, which is widely reported, can only go one way - up. It gives no meaningful insight into how the outbreak has developed says Hans Rosling, professor of global health at the Karolinska Institute in Sweden....

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http://www.bbc.com/news/magazine-30011521

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Health Officials Reassess Strategy to Combat Ebola in Liberia

NEW YORK TIMES                                                         Nov. 13, 2014

By and

WASHINGTON — As the rate of new Ebola infections in Liberia has slowed, American and Liberian officials are debating whether to build all 17 planned Ebola treatment centers in the country or to shift money from the Obama administration that was planned for the centers into other programs to combat future outbreaks.

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Full Senate Committee on Appropriations Hearing on the U.S. Government Response to Ebola Outbreak

               

appropriations.senate.gov - C-SPAN3 - November 12, 2014

Full Committee Hearing on the U.S. Government Response to the Ebola outbreak
 
WHEN:             WEDNESDAY, November 12, 2014 at 2:00 p.m.
                                                                                                             
WHERE:            Room SD-G50 of the Dirksen Senate Office Building

(VIEW THE RECORDED VIDEO IN THE LINKS BELOW)

http://www.appropriations.senate.gov/webcast/full-committee-hearing-us-government-response-fighting-ebola-and-protecting-america

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Ebola: Online briefing now available to the public

 

 

DOCTORS WITHOUT BORDERS                                                                              Nov. 12, 2014

The international medical organisation Médecins Sans Frontières (MSF) or Doctors Without Borders has posted an online briefing on Ebola for aid workers involved in the battle against the haemorrhagic fever. This briefing package is now available to anyone wishing to gain a basic understanding of the virus and how it can be contained.

http://www.msf.org/article/ebola-online-briefing-now-available-public

View the briefing at
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Major Gaps Persist in West African Battle Against Ebola Virus

VOICE OF AMERICA                              Nov. 12, 2014

By Kim Lewis                            

Doctors Without Borders  (MSF) says there have been slight improvements in the Ebola situation in Liberia and Guinea. However, Sierra Leone has experienced a big surge in reported cases throughout the country in recent weeks.

The group released an update on their assessment of the Ebola crisis in the three countries with reports of gains and losses. 

“I think we can see the most improvements in Liberia,” said MSF spokesman James Kambaki. MSF has large isolation center in the country and is distributing an estimated 300,000 protection kits – gloves, masks and chlorine as a disinfectant - to the public. “Besides that, MSF has also done a mass malaria prophylactic prevention to try and ease up the burden of other illnesses so that you can concentrate on Ebola.”

Kambaki said the prevention measures appear to be helping, but MSF is investigating a recent drop in numbers being admitted to their Ebola isolation centers.

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Lawmakers question Obama's $6-billion request for Ebola funding

LOS ANGELES TIMES                                           Nov. 12, 2014
By Matt Hansen
Weighing President Obama’s request for billions of dollars in new funding to combat the Ebola virus, lawmakers on Wednesday pressed federal agencies to explain how the additional money would help in the fight against the disease.

Members of the Senate Appropriations Committee debated Obama’s request for $6.18 billion in additional funds to battle the virus, which has infected more than 13,000 people, mostly in West Africa...

Health and Human Services Secretary Sylvia Mathews Burwell and Homeland Security Secretary Jeh Johnson appear before the Senate Appropriations Committee during a hearing Tuesday in Washington over the government's response to Ebola. (Michael Reynolds / European Pressphoto Agency)

... the request faced skeptical lawmakers who questioned whether additional money would be well spent by a federal government that has struggled at times with containing the epidemic.

“Instead of an effective response, what we’ve witnessed from various agencies is confusing and at times contradictory plans,” Sen. Richard C. Shelby (R-Ala.) said.

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Doctors Without Borders will begin Ebola drug studies by December in Africa

USA TODAY                                         Nov. 12, 2014
by Liz Sazbo

Doctors Without Borders will begin clinical trials of three experimental Ebola therapies in West Africa in December, the aid group announced Wednesday.

The studies, to be conducted at the group's treatment centers in Guinea and Liberia, will test therapies already used in some Ebola patients in the USA and Europe: the antiviral drugs brincidofovir and favipiravir, as well as blood donations from Ebola survivors.

Brincidofovir, made by Chimerix of North Carolina, was given to cameraman Ashoka Mukpo, Liberian national Thomas Eric Duncan and physician Craig Spencer. Mukpo and Spencer survived. Duncan received the drug just a couple days before he died.

Favipiravir, an anti-flu drug made by Japan's Fujifilm Holding Corp., was given to a French nurse who worked with Doctors Without Borders.

And blood donations from Ebola survivors, which contain antibodies against the virus, have been used since the first Ebola outbreak in 1976.

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http://www.usatoday.com/story/news/nation/2014/11/12/ebola-clinical-trial/18919401/

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Ebola death toll tops 5,000; steep rise in Sierra Leone cases

REUTERS                                                                                               Nov. 12, 2014

By Stephanie Nebehay

GENEVA --The death toll from the Ebola outbreak in West Africa's three hardest-hit countries, Guinea, Liberia and Sierra Leone, has risen to 5,147 out of 14,068 cases at the end of Nov. 9, the World Health Organization (WHO) said on Wednesday.

A further 13 deaths and 30 cases have been recorded in five other countries - Nigeria, Senegal, Mali, Spain and the United States, the U.N. agency said.

"There is some evidence that case incidence is no longer increasing nationally in Guinea and Liberia, but steep increases persist in Sierra Leone," the WHO said in a statement. "Cases and deaths continue to be under-reported in this outbreak."

Some 421 new infections were reported in Sierra Leone in the week to Nov. 9, especially in the west and north, it said.

Ebola is still spreading intensely in Sierra Leone's capital of Freetown, with Koinadugu and Kambia northern regions now "emerging areas of concern", it added.

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Ebola crisis: Sierra Leone health workers go on strike

BBC                                                    Nov. 12, 2014

More than 400 health workers involved in treating Ebola patients have gone on strike at a clinic in Sierra Leone.

The staff, who include nurses, porters and cleaners, are protesting about the government's failure to pay an agreed weekly $100 (£63) "hazard payment".

There have been almost 300 new Ebola cases in Sierra Leone in the past three days

The clinic, in Bandajuma near Bo, is the only Ebola treatment centre in southern Sierra Leone.

The Bandajuma clinic is run by medical charity MSF, which said it would be forced to close the facility if the strike continued. MSF's emergency co-ordinator in Sierra Leone, Ewald Stars, told the BBC that about 60 patients had been left unattended because of the strike at the clinic in Bandajuma.
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http://www.bbc.com/news/world-africa-30019895

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U.S. Ebola experience changes thinking about disease

USA TODAY                                   Nov. 11, 2014
By Liz Sazbo
The successful treatment of Westerners with Ebola in the USA and Europe is changing the way doctors think about the disease.

The conventional wisdom about Ebola has been that it's usually fatal, with a mortality rate of up to 90%. That was based largely on experience with Ebola in developing countries in Africa, where many hospitals have no running water and soap, let alone personal protective equipment for the medical staff.

All eight American patients with Ebola treated in the USA have survived. So have most Europeans evacuated to their home countries for care....

With early and aggressive care, "Ebola can be an eminently treatable disease," says Amesh Adalja, senior associate at the Center for Health Security at the University of Pittsburgh Medical Center.

In some ways, Ebola is a different disease in the USA and Europe than it is in Africa, just as cancer is a different disease here than in developing countries, says Jeffrey Duchin, a professor at the University of Washington-Seattle and spokesman for the Infectious Diseases Society of America. Both conditions are fearsome and dangerous, but experience shows that cancer and Ebola can often be survived if caught early and treated aggressively.

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What Employers Are Doing To Counter Ebola

FORBES MAGAZINE                              NOV. 11, 2014
By Tevi Troy, President, American Health Policy Institute

Ebola has killed over 5,000 people, roiled U.S. hospitals, and shaken the faith of Americans in the government’s ability to respond. At the same time, and below the radar, U.S. companies are responding to Ebola with a variety of steps to protect themselves, their employees, and their operations.

The most important element of communicating the threat of the Ebola outbreak for both the government and corporate leaders is to provide factual information while also preventing panic and fear. There have been 5,000 false alarm cases of Ebola as people flock to U.S. emergency rooms out of fear that their common cold or seasonal flu symptoms are early manifestations of the Ebola virus. This hysteria not only has potential mental and physical health implications, but also economic implications. Fear may incentivize some people to change their behavior, whether through cancelling flights and vacation plans or visiting the doctor and stocking up on medications. Furthermore, treating suspected Ebola patients, even if they don’t pan out, is expensive and labor intensive for hospitals.

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Medical Experts Look For New Ways To Test Ebola Drugs

NPR                                             Nov. 11, 2014
By Richard Harris

Medical experts are meeting today and tomorrow at the World Health Organization in Geneva to figure out how to test potential Ebola drugs in Africa. In addition to determining which experimental drugs should be the highest priority, the experts are sorting through some difficult ethical issues.

In short, they're trying to figure out how to design tests that will provide the fastest and most trustworthy answers — and yet minimize the need for comparison groups who won't be offered the experimental treatments.

Nurses assist a new patient at an Ebola center in Liberia's Lofa County. As drug trials get underway, patients may receive experimental medicines. photo by Trenchard/NPR

Practice in the United States has set an unrealistic standard. When American health care workers fell ill with Ebola in Africa, they flew home and received medical care vastly better than what Africans were getting, including experimental therapies.

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Governments, groups striving to become as agile as the Ebola virus

THE WASHINGTON POST                                                                                        Nov. 11, 2014
By Lena H. Sun, Brady Dennis and Joel Achenbach

The news out of West Africa in recent days — good and bad — has demonstrated a fundamental challenge in the fight against Ebola: The virus is more nimble than the human response to it. The landscape of infection and disease has changed dramatically in recent weeks, even as institutions have largely stuck to blueprints drafted months ago.

Archie C. Gbessay, coordinator of the Active Case Finders and Awareness Team in West Point, a large slum in Monrovia, Liberia, discusses efforts to combat Ebola with his team in a school classroom in September. (Michel du Cille/The Washington Post)

The looming question now is whether governments and other organizations can find a way to become as agile as the virus, which has vanished suddenly in some hard-hit places while erupting just as quickly in new locations.

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